Tirzepatide Reconstitution Chart: 5mg to 60mg Vials in Units

Tirzepatide Reconstitution Chart: All Vial Sizes, All Doses

This is the master table. Each row is a vial size paired with its recommended BAC water volume and the concentration that produces. Each column is a titration dose. The cell value is the units you draw on a standard U-100 insulin syringe. The starred row (30mg + 3mL) is the most common compounding setup because it makes every dose a round number.

All values calculated using IU = (dose_mg / concentration_mg_per_mL) x 100, drawn on a standard U-100 insulin syringe where 100 units equals 1mL. n/a = the requested dose exceeds the total amount of tirzepatide in this vial (a physically impossible draw at any concentration). Separately, any value over 100 units is a possible dose that simply cannot be drawn in one standard 1mL U-100 syringe: split it into two draws or use a larger syringe. See the Syringe Capacity Guide below for the per-concentration limits.

How to Read This Chart

Find the row that matches your vial size and how much BAC water you added. Move across to the column for the dose your protocol calls for this week. The number in that cell is the mark you draw to on a U-100 insulin syringe, where 100 units equals 1mL. If your exact vial and water combination is not in the table, run it through the tirzepatide calculator for the precise units.

The Recommended Setup: 30mg Vial + 3mL BAC Water

Most people compounding tirzepatide land on the 30mg vial with 3mL of bacteriostatic water. That produces 10mg/mL, where every step in the standard titration is a clean, round number: 2.5mg is 25 units, 5mg is 50, 7.5mg is 75, and 10mg fills exactly 100 units. The two highest steps, 12.5mg (125 units) and 15mg (150 units), exceed a single 1mL syringe at this concentration, so they need a 1.5mL syringe or a split draw, but they remain practical. This single setup carries you cleanly from the starting dose of 2.5mg through most of the titration, which is why most compounding instructions default to it.

Vial-by-Vial Breakdown

The chart compresses everything into one grid. This section unpacks each vial size so you can see which one fits your protocol. For the actual mixing procedure, sterile technique, and equipment list, see the tirzepatide reconstitution guide.

The reconstitution lookup at a glance: vial size on the left, dose across the top, units in the cells.

5mg and 10mg Vials: Starter or Trial Sizes

A 5mg vial with 1mL of BAC water gives 5mg/mL. A 10mg vial with 2mL also gives 5mg/mL. Both handle a 2.5mg dose (50 units) and a 5mg dose (100 units, which fills a 1mL syringe exactly). Neither works above 5mg at this concentration without overflowing the syringe. These are trial or starter vials: a 5mg vial holds only two 2.5mg doses or one 5mg dose, so most people move to a larger vial once they are tolerating treatment.

15mg Vial: Early Titration

A 15mg vial with 3mL of BAC water also produces 5mg/mL. It covers 2.5mg (50 units), 5mg (100 units), and 7.5mg (150 units, which needs a larger syringe). The same overflow constraint applies above 5mg on a standard 1mL syringe. This size suits people who stop at a low maintenance dose and want fewer reconstitutions than the small vials require.

30mg Vial: The Standard Choice

The workhorse. Add 3mL of BAC water for 10mg/mL and the full titration is in reach: 2.5mg = 25 units, 5mg = 50, 7.5mg = 75, 10mg = 100. The two top steps (12.5mg and 15mg) read 125 and 150 units, which exceed a 1mL syringe and need a 1.5mL syringe or a split draw. Here is the 30mg row on its own, for anyone who only wants to screenshot this section:

45mg and 60mg Vials: Bulk Supply

A 45mg vial with 3mL of BAC water gives 15mg/mL. A 60mg vial with 3mL gives 20mg/mL. Both are concentrated, so draw volumes are small: at 20mg/mL, even a 15mg dose is only 75 units. These sizes suit people who buy in bulk and want fewer vials to reconstitute over a long protocol. The trade-off is precision. At high concentration a small reading error on the syringe maps to a larger error in milligrams, so draw carefully and use a syringe with clear graduations.

Syringe Capacity Guide

A standard 1mL U-100 insulin syringe holds a maximum of 100 units. When a dose maps to more than 100 units you have exceeded the syringe and need a 1.5mL syringe, a 3mL syringe, or a split draw across two injections. Concentration decides where that ceiling lands.

Reading a U-100 syringe: 25 units is 2.5mg at 10mg/mL, 50 units is 2.5mg at 5mg/mL.

The practical takeaway: if you want every titration step to fit in one standard syringe, a higher concentration helps, but it also shrinks the draw volume and makes small reading errors matter more. The 30mg + 3mL setup at 10mg/mL is the usual compromise, clean numbers through 10mg with only the top two steps needing a bigger syringe.

Storage After Reconstitution (Quick Reference)

That covers the essentials for the chart. For the full storage protocol and handling detail, see the tirzepatide reconstitution guide.

Use the Calculator for Custom Combinations

The chart on this page covers every standard vial and BAC water setup. If your configuration is non-standard, for example a 20mg vial with 2mL of water or an unusual dose between titration steps, the free calculator returns the exact units instantly. Enter your vial size, your BAC water volume, and your target dose.

Video Walkthrough

To see the reconstitution and the unit math demonstrated alongside the chart, this walkthrough from a wellness clinic covers both tirzepatide and semaglutide. Follow your pharmacy's instructions and the linked reconstitution guide for the exact procedure.