How often should you inject Ozempic?

Ozempic is typically injected once weekly due to its long half-life of approximately 7 days.

How long until Ozempic reaches steady state?

With a half-life of approximately 7 days, Ozempic reaches steady state after about 4-5 weeks of consistent weekly dosing. Steady state means drug levels stabilize with consistent peaks and troughs.

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Average stable amount: - mg

Stable window days

Date	Day	Amount in Body

Ozempic Calculator: Track Dose Levels & Reach Steady State

// HOW IT WORKS

How the Ozempic Calculator Works

This free Ozempic calculator uses pharmacokinetic modeling to track your semaglutide levels over time. Enter your dose and schedule to see how the drug builds up in your system.

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Ozempic Half-Life Calculator

With a 7-day half-life, see exactly how concentration peaks after each injection and decreases over the week.

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Steady State Prediction

Know when you'll reach steady state (typically 4-5 weeks on Ozempic) where drug levels stabilize.

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Visualize Drug Levels

Interactive chart shows semaglutide concentration from your first dose through your target maintenance dose.

Ozempic Dosing Guide

Ozempic (semaglutide) is an FDA-approved once-weekly injectable medication for type 2 diabetes management. It works by mimicking GLP-1, a hormone that regulates blood sugar and reduces appetite. The standard dosing protocol follows a gradual titration schedule starting at 0.25mg weekly. Ozempic has a maximum approved dose of 2mg weekly for diabetes management. With a half-life of approximately 7 days, Ozempic reaches steady state after about 4-5 weeks of consistent dosing.

Standard Ozempic Dosage Chart

Tier	Weekly Dose	Duration	Pen Type
1	0.25 mg	4 weeks	Red pen (0.25/0.5mg)
2	0.5 mg	4 weeks	Red pen (0.25/0.5mg)
3	1.0 mg	4+ weeks	Blue pen (1mg)
4	2.0 mg	Maintenance	Yellow pen (2mg)

Key Facts About Ozempic

Active Ingredient: Semaglutide
Half-life: Approximately 7 days
FDA Approval: Type 2 Diabetes (2017)
Maximum Dose: 2mg weekly
Administration: Once weekly subcutaneous injection
Pen Options: 0.25/0.5mg (red), 1mg (blue), 2mg (yellow)

Ozempic vs Wegovy

Ozempic and Wegovy contain the same active ingredient (semaglutide) but are approved for different indications. Ozempic is approved for type 2 diabetes with a maximum dose of 2mg, while Wegovy is approved for chronic weight management with a maximum dose of 2.4mg.

Note: Individual dosing may vary. Always follow guidance from your healthcare provider.

// FAQ

Ozempic Calculator FAQ

What is the half-life of Ozempic?

Ozempic (semaglutide) has a half-life of approximately 7 days. This means after one week, about 50% of the drug remains in your system. This long half-life is why Ozempic is dosed once weekly for diabetes management.

How long does Ozempic stay in your system?

After stopping Ozempic, it takes approximately 5 half-lives (about 35 days or 5 weeks) for the drug to be essentially cleared from your system. Blood sugar effects may continue during this washout period.

When do I reach steady state on Ozempic?

You reach steady state after approximately 4-5 weeks of consistent weekly dosing at the same dose level. At steady state, blood sugar control becomes more predictable as drug levels stabilize.

Get started in seconds with our pre-built titration templates, or build your own custom schedule below.

Statistics

Peak Amount

Today's Amount

Average Stable Amount

Days until stable Click to learn how stability is calculated

Total Administered Complete Plot

Total Administered so far

Out of System (<0.02mg)

Weight Trend

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Drug Amount Plot

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Generate a schedule and click "Generate Plot" to visualize

What's a half-life?

The time your body needs to clear half a dose. After about five half-lives, a single dose is essentially gone. Tirzepatide has a half-life of roughly 5 days, so one dose takes about 25 days to clear; Semaglutide is closer to 7 days; Retatrutide is about 6 days.

Read the full half-life guide

What's steady state?

The point where what you take in each week equals what your body clears. Most weekly GLP-1s reach it after 4–5 weeks of consistent dosing — that's when blood levels stop climbing and the chart flattens out.

Read the full steady-state guide

Dose Schedule

Week	/Week	Date	Day	Time	Vial	IU	Dose (mg)	Weight (kg)	Journal	Actions

Configure your schedule below and click "Generate Schedule" to begin

Configure Dose Schedule

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