Resources & Guides
Educational content about GLP-1 medications, pharmacokinetics, and optimizing your treatment journey.
GLP-1 Medication Hubs
Comprehensive guides for each GLP-1 medication—dosing protocols, clinical trial data, microdosing strategies, and our free calculators.
Semaglutide Guide
Ozempic & Wegovy: GLP-1 receptor agonist. ~15% weight loss, 7-day half-life. FDA-approved for diabetes and weight management.
Tirzepatide Guide
Mounjaro & Zepbound: Dual GLP-1/GIP agonist. ~21% weight loss, 5-day half-life. The first dual-agonist approved by FDA.
Retatrutide Guide
Triple GLP-1/GIP/Glucagon agonist. ~24% weight loss in trials, 6-day half-life. Expected FDA approval 2027.
Educational Content
What Is Retatrutide? Complete Guide to the Triple-Agonist Weight Loss Drug
articleRetatrutide is an investigational triple-agonist medication that activates GLP-1, GIP, and glucagon receptors. Phase 2 trials showed 24.2% weight loss, the highest ever recorded for a GLP-1 class drug. Learn everything about this breakthrough medication.
Best Time to Take Retatrutide: Day, Time, and Meals
guidesA pharmacokinetics-backed guide to retatrutide injection timing: why the ~6-day half-life makes time of day flexible, how to pick a consistent weekly injection day, the morning-versus-evening trade-offs, meal timing on injection day, and bloodwork logistics.
How to Inject Retatrutide: Step-by-Step Technique Guide
articleA step-by-step guide to the retatrutide injection technique, from drawing your dose to sharps disposal. Covers vial-and-syringe and pen formats, needle angle, the pinch, and site rotation, based on the published trial literature and standard subcutaneous injection practice.
When Will Retatrutide Be FDA Approved? Timeline, Trials & Projections (2026)
articleA current read on the retatrutide FDA timeline. The molecule is still investigational, Lilly plans to submit a Biologics License Application (BLA) in Q1 2027, and the most defensible approval window is late 2027 to 2028. Here is what TRIUMPH Phase 3 has reported, what happens next, and how the timeline compares with tirzepatide.
Retatrutide Injection Sites: Where to Inject and How to Rotate
educationRetatrutide (LY3437943) is injected subcutaneously once weekly into one of three DailyMed-confirmed sites: abdomen, thigh, or upper arm. This guide covers each site, how to rotate with every dose, what the label requires for prep, and which local reactions to watch for.