GLP-1 Dosing Scenarios
Pre-computed pharmacokinetic data for common dosing protocols. Each page shows drug levels, peak/trough values, time to steady state, and reconstitution math from the same model as the calculators. The methodology lists each parameter's source and marks the assumptions, including retatrutide's bioavailability.
Retatrutide
Retatrutide Standard Titration: 2mg to 12mg Weekly Protocol
See how retatrutide levels build during the standard 2mg to 12mg titration. Pre-computed pharmacokinetic data showing peak levels, trough levels, and time to steady state at each dose tier.
standardRetatrutide Conservative Titration: 1mg Start, Slow Escalation
Conservative retatrutide titration starting at 1mg weekly with slower dose increases. Pre-computed PK data showing drug accumulation at each step.
standardRetatrutide Microdosing: Split Dose Protocol (2x per Week)
How split dosing affects retatrutide blood levels compared to once-weekly injection. Pre-computed PK curves for 2x/week microdosing at equivalent total weekly doses.
microdoseRetatrutide Dose Change: What Happens Going from 4mg to 8mg
What happens to your retatrutide blood levels when you increase from 4mg to 8mg weekly. Pre-computed PK data showing the transition period, new steady state, and how long it takes to stabilize.
transitionRetatrutide Missed Dose: What Happens If You Skip a Week
What happens to your retatrutide blood levels if you miss a weekly dose. Pre-computed PK data showing the drop, recovery, and how long it takes to get back to steady state.
transitionRetatrutide Washout: How Long Until It Leaves Your System
How long retatrutide stays in your system after your last dose. Pre-computed PK curve showing the modelled level falling after the last dose.
washoutSemaglutide
Semaglutide Standard Titration: 0.25mg to 2.4mg Weekly
Semaglutide (Ozempic/Wegovy) standard titration schedule with pre-computed pharmacokinetic data. See how levels build from 0.25mg to the 2.4mg maintenance dose.
standardSemaglutide Microdosing: Low-Dose Maintenance Protocol
Low-dose semaglutide maintenance protocol at 0.125-0.5mg weekly. Pre-computed PK data showing steady-state levels and how they compare to standard therapeutic doses.
low doseSemaglutide Dose Change: 1mg to 2.4mg Transition
What happens to semaglutide blood levels when jumping from 1mg to 2.4mg weekly. Pre-computed PK data showing new peak, trough, and time to new steady state.
transitionSemaglutide Washout: How Long Until Ozempic Leaves Your System
How long semaglutide (Ozempic/Wegovy) stays in your system after your last injection. Pre-computed PK curve showing the modelled level falling after the last dose.
washoutTirzepatide
Tirzepatide Standard Titration: 2.5mg to 15mg Weekly
Tirzepatide (Mounjaro/Zepbound) standard titration from 2.5mg to 15mg weekly. Pre-computed pharmacokinetic data showing drug accumulation and steady state at each dose.
standardTirzepatide Split Dosing: 2x Per Week Protocol
How splitting tirzepatide into two injections per week affects blood levels compared to once-weekly dosing. Pre-computed PK comparison curves.
microdoseTirzepatide Dose Change: 5mg to 10mg Transition
What happens to tirzepatide blood levels when increasing from 5mg to 10mg weekly. Pre-computed PK curves showing the transition to new steady state.
transitionTirzepatide Washout: How Long Until Zepbound Leaves Your System
How long tirzepatide (Zepbound/Mounjaro) stays in your system after stopping. Pre-computed PK curve showing the modelled level falling after the last dose.
washout