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Retatrutide Clinical Trial Near Me: How to Find and Enroll (2026)

How to find a retatrutide clinical trial near you in 2026. Search ClinicalTrials.gov, check eligibility, contact a site, and questions to ask before you enroll.

Map of the United States with violet pin markers showing where to find a retatrutide clinical trial near you.

Searching "Retatrutide Clinical Trial Near Me"? Start Here

Retatrutide is not FDA-approved and cannot be obtained by prescription. As of mid-2026, joining a clinical trial is the main way to receive Eli Lilly-manufactured retatrutide under medical supervision; the only other lawful route is Lilly's narrow expanded access program for patients who cannot join a trial. Because trials run at sites scattered across the country, finding a retatrutide clinical trial near me starts with knowing where to search and how to read what you find. This guide walks through every step, from checking your eligibility to contacting a study coordinator.

Key Takeaways

  • A trial is the main legal route: Retatrutide remains investigational, so a clinical trial is the main way to receive verified, Lilly-manufactured drug. The only other legal route is Lilly's narrow expanded access program, which a treating physician must request.
  • TRIUMPH-1 has closed: The main obesity trial (NCT05929066) completed enrollment in April 2026. Do not try to join it; search for studies that are currently recruiting instead.
  • Search by status and location: On ClinicalTrials.gov, filter by Status "Recruiting" and your ZIP code to surface only open trials near you.
  • Eligibility varies by trial: The obesity arm typically required a BMI of 30 or higher (or 27 with a comorbidity). Other trials use different thresholds.
  • You may receive placebo: All TRIUMPH trials are double-blind and placebo-controlled, so enrollment does not guarantee the active drug.
5,800+
TRIUMPH participants
Phase 3
Current stage
$0
Cost of trial drug
BMI 30+
Typical obesity arm

Investigational Status

Retatrutide (LY3437943) is not FDA-approved. It is an investigational triple-agonist developed by Eli Lilly, currently in Phase 3 trials under the TRIUMPH program. There is no commercially available, prescription version. Anything sold online as retatrutide outside a trial is not Lilly-manufactured drug. For official trial information, see ClinicalTrials.gov.

What Is the TRIUMPH Program? (30-Second Orientation)

TRIUMPH is the name Eli Lilly gives to its Phase 3 retatrutide trial program. The rationale and design across its trials were described by Giblin and colleagues in Diabetes, Obesity and Metabolism in 2026 (PMID 41090431). Across the program, more than 5,800 participants have been enrolled in studies spanning obesity, sleep apnea, knee osteoarthritis, cardiovascular outcomes, and weight maintenance.

If you join a retatrutide study, you are joining one of these trials. You do not need to memorize the program to enroll, but knowing the major studies helps you read trial listings and recognize which one a site is running. For the full results-focused breakdown, see our TRIUMPH program overview.

Which Retatrutide Trials Are Still Recruiting?

Update, October 2, 2026: no TRIUMPH trial is recruiting any more. The retatrutide studies open on ClinicalTrials.gov are NCT07165028 (Phase 3, fatty liver disease) and NCT07467447 (Phase 2, obesity). This is the most time-sensitive part of any trial search, because recruitment status changes month to month. The snapshot below reflects ClinicalTrials.gov as of June 2026. Always confirm the live status yourself before contacting a site.

Trial NCT Number Focus Status (June 2026)
TRIUMPH-1 NCT05929066 Obesity, no type 2 diabetes Completed enrollment
TRIUMPH-3 NCT05882045 Severe obesity + established CVD Active, not recruiting
TRIUMPH-Outcomes NCT06383390 Cardiovascular and kidney outcomes Active, not recruiting
TRIUMPH-6 NCT06859268 Weight maintenance (Phase 3b) Active, not recruiting
SYNERGY-Outcomes NCT07165028 Retatrutide and tirzepatide in high-risk MASLD Recruiting

The main trials that enrolled the general obesity population, including TRIUMPH-1, have now completed enrollment. Lilly continues to run multiple retatrutide studies, and new trials can open at any time. The search process below will surface any study that is currently recruiting near you, including newer protocols not listed above.

Am I Eligible? Who TRIUMPH Trials Typically Enroll

Every trial sets its own inclusion and exclusion rules, but the general obesity arm gives a useful baseline for self-screening before you invest time in an application. The criteria below describe the typical profile based on TRIUMPH-1, verified against ClinicalTrials.gov in June 2026. They are not universal for all trials.

Retatrutide trial eligibility: typically included criteria versus typically excluded criteria, verified June 2026.

Who Is Typically Included

  • Adults 18 years of age and older
  • BMI of 30 kg/m² or higher (obesity), or BMI of 27 kg/m² or higher with at least one weight-related condition such as hypertension, dyslipidemia, sleep apnea, or cardiovascular disease
  • No type 2 diabetes (TRIUMPH-1 specifically excluded diabetes; other trials differ)
  • A history of unsuccessful weight loss through diet and lifestyle changes

Common Reasons People Are Excluded

  • Personal or family history of medullary thyroid carcinoma (MTC) or MEN syndrome type 2
  • Prior pancreatitis
  • A type 2 diabetes diagnosis (for the obesity-only arm)
  • Body weight change greater than 5 kg in the 90 days before screening
  • Use of any weight-loss medication within the prior 90 days
  • Recent cardiovascular events, which are handled differently in the cardiovascular trials

If you have type 2 diabetes: Lilly has tested retatrutide in diabetes through a separate study program, but the obesity-focused TRIUMPH-1 trial excluded diabetes. Different trials apply different rules, so search ClinicalTrials.gov and the Lilly trial finder rather than assuming you are ruled out. Only a site coordinator can confirm eligibility for a specific protocol.

Track Your Retatrutide Schedule

If you do access retatrutide through a trial or another route, use our free calculator to model dosing and steady-state levels over time.

How to Search for a Retatrutide Clinical Trial Near Me: Step by Step

There are two reliable starting points: the federal ClinicalTrials.gov registry and Eli Lilly's own trial finder. ClinicalTrials.gov is the most comprehensive; the Lilly finder is the easiest to use and can alert you when a new study opens nearby.

Five-step ClinicalTrials.gov search flow for finding a recruiting retatrutide trial near your ZIP code.

Method 1: ClinicalTrials.gov (Most Comprehensive)

  1. Go to ClinicalTrials.gov and click "Find a Study."
  2. In the search box, type retatrutide (or the molecule ID, LY3437943).
  3. Under "Status," select Recruiting so you see only trials with open enrollment.
  4. Under "Location," enter your ZIP code or city and choose a search radius such as 100 miles.
  5. Review each result: read the "Brief Summary," then open the "Eligibility" tab.
  6. Click "Contacts and Locations" to find the nearest site with open slots.
  7. Use the email or phone shown. This reaches the site coordinator, not Lilly's head office.

What the status labels mean:

  • Recruiting means the trial is actively seeking participants now.
  • Active, not recruiting means the trial is running but enrollment is closed.
  • Completed means the trial has finished; no enrollment is possible.
  • Not yet recruiting means the trial is registered but has not started.

Method 2: Eli Lilly's Trial Finder

Lilly runs its own location-aware trial finder. It only shows Lilly-sponsored studies, but since retatrutide is exclusively a Lilly compound, that limitation does not matter here. The interface is friendlier for non-researchers, and you can sign up for alerts so Lilly notifies you when a matching trial opens near you. Search "retatrutide," enter your ZIP code, and opt in to alerts.

What to Do If No Trial Is Near You

  • Sign up for alerts on the Lilly trial finder so you hear about new sites first.
  • Ask your primary care physician or endocrinologist whether they know of local research sites.
  • Consider whether traveling is feasible. Some participants drive one to three hours for trials with infrequent visits.
  • Contact major academic medical centers and university hospitals in your region and ask if they are running a TRIUMPH study.

What Happens After You Contact a Trial Site?

Knowing the funnel ahead of time means nothing catches you off guard. The exact timeline varies by site, but the sequence is consistent.

  1. Pre-screen call or form. The coordinator asks basic eligibility questions by phone or online. This usually takes 10 to 20 minutes.
  2. Screening visit. A clinic visit for bloodwork, vitals, BMI measurement, and a medical history review. Plan for a few hours.
  3. Eligibility decision. The site reviews your screening results against the inclusion and exclusion criteria, which can take one to four weeks.
  4. Informed consent and randomization. If eligible, you review a detailed consent document covering all risks, then a computer assigns you to the drug or placebo arm.
  5. Treatment and follow-up. You receive injections and attend periodic visits. Ask the site for the exact schedule, since it differs by trial.

What Clinical Trial Participation Actually Involves

The Placebo Reality

All current TRIUMPH trials are double-blind and placebo-controlled. Depending on the study, somewhere between one in three and one in two participants may receive placebo, and neither you nor your study team knows which arm you are in during the trial. This design is standard for Phase 3 studies and is ethically required to produce reliable results.

Costs and Compensation

The investigational drug is always provided at no cost in a sponsored trial, and you should never be charged to participate. Most sites reimburse for travel and time, but compensation and visit schedules vary by site, so ask the study coordinator about their specific policy before enrolling. Do not treat a clinical trial as an income source; the goal is research participation with medical supervision, not pay.

How Long Will It Take?

TRIUMPH-1 ran for 80 weeks, roughly 18 months. Newer trials may have different durations. Expect a multi-month commitment with periodic clinic visits. Participation is voluntary, and you can withdraw at any time without penalty.

Video: Retatrutide Phase 3 Results in Context

Before enrolling, it helps to understand what the program has shown so far. This breakdown of the Phase 3 TRIUMPH data gives useful context on what participants are contributing to.

Questions to Ask the Trial Site Coordinator

Copy this checklist and bring it to your pre-screen call. A good coordinator will answer all of these without hesitation.

  1. Are you actively accepting new participants right now?
  2. What are the exact inclusion and exclusion criteria for this trial?
  3. How many clinic visits are required, and at what intervals?
  4. Is there a placebo arm, and what is the randomization ratio?
  5. What is your reimbursement or compensation policy for visits?
  6. Are virtual visits or telephone check-ins available for any appointments?
  7. What happens to my treatment after the trial ends, and can I continue on the drug?
  8. Who do I contact if I experience side effects between visits?
  9. Is there a screening fee, and what does the initial visit involve?
  10. If I qualify, what is the earliest I could start?

What Results Have Been Announced So Far?

Knowing what retatrutide has shown so far helps you weigh whether to participate. The figures below come from published and reported trial data.

  • Phase 2 (NEJM, 2023, n=338, 48 weeks): up to 24.2% average body-weight loss on the 12mg dose.
  • TRIUMPH-4 (NCT05931367, 68 weeks, obesity and knee osteoarthritis): 28.7% average weight loss on 12mg versus 2.1% on placebo.
  • TRIUMPH-1 (NCT05929066, n=2,339, 80 weeks, general obesity): 28.3% average weight loss on the 12mg dose.

For the full dose-by-dose breakdown, see our retatrutide Phase 3 results page.

A realistic expectation: Trial averages do not guarantee personal outcomes. FDA approval has not been granted, and joining a trial does not guarantee you will receive the active drug rather than placebo.

What If You Cannot Qualify or Enroll?

If you cannot join a trial, the only other lawful path is Lilly's expanded access program, which runs before FDA approval "for a limited number of patients who meet specific medical criteria and cannot enroll in a clinical trial" (Reuters via KSL). Patients must be 18 or older with a BMI of 35 or more despite tolerating the highest available dose of weight-management therapy, have two or more serious or life-threatening obesity-related complications, be unable to join an ongoing retatrutide (or comparable) trial, and have discussed all standard treatment options, including bariatric surgery, with their doctor (Lilly Medical; ClinicalTrials.gov NCT07629401). The treating physician applies to the FDA as the sponsor of a patient-specific investigational new drug (IND) application and must obtain institutional review board (IRB) approval. Lilly provides the drug at no cost, and direct-to-patient shipping is not available. It is not something a patient can buy. Outside these two routes, there is no lawful path to retatrutide. The FDA states retatrutide cannot be used in compounding under federal law, so compounding pharmacies cannot lawfully supply it. Research peptide vendors sell it labeled "not for human use," and the FDA has warned companies that illegally sold retatrutide labeled "for research purposes" or "not for human consumption." Neither source provides Lilly's pharmaceutical-grade product or quality controls. Our guide on how to get retatrutide compares the routes people mention, compounded retatrutide explains the compounding ban, and retatrutide vs tirzepatide covers an FDA-approved alternative you can use while you wait.

Frequently Asked Questions

Is retatrutide still in clinical trials?

Yes. As of mid-2026, Eli Lilly's TRIUMPH program includes multiple active retatrutide studies. TRIUMPH-1, the main obesity trial (n=2,339), completed enrollment and reported results in May 2026. Other studies, including the cardiovascular outcomes trial (TRIUMPH-Outcomes, NCT06383390), remain active, and new trials may be recruiting. Search ClinicalTrials.gov for the current list.

How much does it cost to join a retatrutide clinical trial?

Nothing for the investigational drug, which is always provided at no charge in a sponsored trial. Most sites also reimburse for travel and time, though the amount varies by site. Ask the coordinator for their specific policy. You should never be charged to participate in a sponsored clinical trial.

Can I get retatrutide now, outside of a clinical trial?

Only in narrow cases. In the US, apart from a clinical trial, the only other lawful route is Lilly's expanded access program, which a treating physician must request for adults with a BMI of 35 or more who meet strict criteria (including two or more serious obesity-related complications) and cannot join a trial. The FDA states retatrutide cannot be used in compounding under federal law, so compounding pharmacies cannot lawfully supply it. Research peptide vendors sell it labeled not for human use, and the FDA has warned companies for illegally selling it that way. See our guide to how to get retatrutide for a full comparison.

What BMI do I need to qualify for a retatrutide trial?

TRIUMPH-1, the main obesity trial, required a BMI of 30 kg/m² or higher, or 27 or higher with a weight-related condition such as hypertension, dyslipidemia, sleep apnea, or cardiovascular disease. Other trials use different thresholds; TRIUMPH-3 required a BMI of 35 or higher. Always check the specific trial's eligibility criteria on ClinicalTrials.gov.

How can I get into a clinical trial for retatrutide?

Search ClinicalTrials.gov for retatrutide, filter by Status "Recruiting" and your location, and sign up for alerts on the Lilly trial finder. If a study is near you, contact the site coordinator listed under "Contacts and Locations." Expect a pre-screen call, a screening visit, and an eligibility decision before enrollment.

What disqualifies you from retatrutide trials?

Common exclusions across TRIUMPH trials include a personal or family history of medullary thyroid carcinoma or MEN syndrome type 2, prior pancreatitis, a body-weight change greater than 5 kg in the 90 days before screening, and use of weight-loss medications within 90 days. TRIUMPH-1 also excluded type 2 diabetes. Each trial sets its own criteria, so review the eligibility tab on each listing.

Will I definitely get retatrutide if I join a trial?

Not necessarily. All TRIUMPH trials are double-blind and placebo-controlled, so depending on the randomization ratio you may receive placebo instead of the active drug. You will not be told which arm you are in during the trial. This is a standard and ethically required feature of Phase 3 studies.

How long does a retatrutide clinical trial last?

TRIUMPH-1 ran for 80 weeks, about 18 months, and TRIUMPH-4 ran 68 weeks. Newer trials may differ. Expect a substantial time commitment with periodic clinic visits. You can withdraw at any time without penalty.

What are the alternatives if I cannot get into a trial?

Tirzepatide (Zepbound and Mounjaro) is FDA-approved and available by prescription, with Phase 3 data showing up to 20.9% weight loss at 72 weeks. Semaglutide (Wegovy) is also approved. Both are established options in the GLP-1 drug class: tirzepatide is a dual GLP-1/GIP agonist, while semaglutide is a GLP-1 receptor agonist. See our retatrutide vs tirzepatide comparison for a side-by-side look.

Plan Your Retatrutide Dosing

Whether you enroll in a trial or access retatrutide another way, model your schedule and steady-state levels with our free calculator.

References

  1. ClinicalTrials.gov. A Master Protocol to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants Without Type 2 Diabetes Who Have Obesity or Overweight (TRIUMPH-1). NCT05929066. Eli Lilly and Company. [ClinicalTrials.gov]
  2. ClinicalTrials.gov. A Phase 3 Study to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee (TRIUMPH-4). NCT05931367. Eli Lilly and Company. [ClinicalTrials.gov]
  3. ClinicalTrials.gov. A Phase 3 Study of LY3437943 in Participants With Severe Obesity and Established Cardiovascular Disease (TRIUMPH-3). NCT05882045. Eli Lilly and Company. [ClinicalTrials.gov]
  4. ClinicalTrials.gov. The Effect of Retatrutide Once Weekly on Cardiovascular and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes). NCT06383390. Eli Lilly and Company. [ClinicalTrials.gov]
  5. ClinicalTrials.gov. A Phase 3b Study to Evaluate Retatrutide Treatment in the Maintenance of Weight Reduction in Individuals With Obesity (TRIUMPH-6). NCT06859268. Eli Lilly and Company. [ClinicalTrials.gov]
  6. ClinicalTrials.gov. A Study of Retatrutide and Tirzepatide in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease at High Cardiovascular Risk (SYNERGY-Outcomes). NCT07165028. Eli Lilly and Company. Recruiting as of June 2026; confirm live status before contacting a site. [ClinicalTrials.gov]
  7. Giblin K, Kaplan LM, Somers VK, et al. Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: rationale and design of the TRIUMPH registrational clinical trials. Diabetes Obes Metab. 2026;28(1):83-93. [PubMed]
  8. Jastreboff AM, Kaplan LM, Frías JP, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity: A Phase 2 Trial. N Engl J Med. 2023;389(6):514-526. [PubMed]

Medical Disclaimer

This article is for informational and educational purposes only and does not constitute medical advice. Retatrutide is an investigational medication not yet approved by the FDA. Clinical trial participation carries risks, and eligibility can only be confirmed by a qualified study team. Do not start, stop, or modify any medication regimen without consulting a qualified healthcare provider. Always discuss risks, benefits, and alternatives with your doctor.